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RR426 - A methodology to prioritise substances for possible further development of Acute Exposure Threshold Levels (AETLs)

The aim of the Acute Exposure research project, ACUTEX, is to develop a methodology for establishing European Acute Exposure Threshold Levels, AETLs, for toxic substances in relation to harm to people by inhalation. The development of AETLs is initially in the context of the risks of major accidents from chemical sites and in particular their regulation through the EU ‘Seveso II’ Directive. It is intended that AETLs can be used within Member States, where appropriate, to inform decisions on land-use planning and emergency planning.

This report describes the development of a prioritisation methodology to inform initial substance selection for a possible further AETLs programme. The work was based on consultation with experts drawn from EU major stakeholder groups. It included a Validation Exercise working with 3 Member States which account for between approximately 40% and 50% of all EU Seveso II sites. From this Validation Exercise we infer that, if these three Member States are representative in terms of numbers of priority substances, then the number of EU higher priority substances for further AETLs development is unlikely to be much in excess of 50.

This report and the work it describes were funded by the Health and Safety Executive (HSE). Its contents, including any opinions and/or conclusions expressed, are those of the authors alone and do not necessarily reflect HSE policy.

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Updated 2019-08-27