RR300 - Development of a field method for the assessment of the effectiveness of barrier creams in preventing skin irritation reactions

This report presents findings of a study designed to develop a field test method using non-invasive
bioengineering skin instrumentation for evaluating the effectiveness of a barrier cream against
chemical skin irritants used in a typical work place setting. Both the baseline and test protocols
developed can be easily adopted in different industrial settings and used to evaluate other barrier
creams (BCs) for different substances used on industrial sites. The instruments and test protocols used here showed that the BC we evaluated was effective in protecting the skin from a strong skin irritant SLS) and one of the two oils used on site. Of the instruments used in the factory setting, the
Chromameter and the TEWL provided the most reliable and stable data.

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