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Safe working and the prevention of infection in clinical laboratories and similar facilities Second edition 2003 ISBN 0 7176 2513 3

  1. Erratum: Table 2 on page 35 contains a typographical error. The holding time for make safe at 134 OC should read 3 minutes.
  2. Amendment: Carriage of specimens by road paras. 183 – 186 and Appendix 3. The Certificate of Exemption referred to in para. 183 and reproduced in Appendix 3 expired on 31 December 2003. Interim certificates of Exemption have been issued and will be withdrawn when the revised Carriage of Dangerous Goods Regulations come into force (expected April 2004) Further information can be found on the carriage of dangerous goods web pages
  3. Amendment: Requirement to maintain laboratory workplaces at negative pressure. Table 1 on page 13 states that CL2 laboratories should be maintained at negative pressure to atmosphere, if mechanically ventilated. This was based on the requirements of COSHH 1999. At the time this guidance going to publication, the requirements of COSHH 2002 were not finalised. The requirement for a CL2 facility to be maintained at negative pressure was removed in COSHH 2002. It is important, nevertheless, to ensure that the laboratory cannot become positively pressurised with respect to the surrounding environment. The requirements to maintain CL3 and CL4 laboratories at negative pressure with respect to atmosphere remain unchanged.